Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Pathophysiology and the Role of Catheter Ablation
AF in HFpEF
Abstract
Atrial fibrillation (AF) and heart failure (HF) often coexist, and the prognosis of patients who have both these conditions is worse than those with either condition alone. Heart failure with preserved ejection fraction (HFpEF) is a clinical condition that was initially characterized as diastolic dysfunction HF, then as HF with normal ejection fraction, and more recently as HFpEF. About one-third of patients with HFpEF suffer from AF. Although, both clinical entities share common pathophysiologic mechanisms, current knowledge of the relationship between AF and HFpEF is limited. Catheter ablation, although data from randomized trials in this category of patients are limited, seems to have beneficial effects regarding maintenance of sinus rhythm and re-hospitalization rates. Rhythmos 2020;15(2):29-32.
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