Lethal Proarrhythmic Effect of Propafenone
Keywords:
propafenone, antiarrhythmic drugs, proarrhythmia, wide-complex tachycardia, atrial flutter, atrial fibrillationAbstract
A 67-year-old man with history of paroxysmal atrial fibrillation and known ischemic cardiomyopathy, dyslipidemia, hypertension, and chronic renal failure, was admitted via the emergency room with complaints of palpitations. Past medical history was remarkable for prior myocardial infarction in 2007 followed by percutaneous coronary intervention in the left anterior descending and right coronary arteries. Recent echocardiography showed a left ventricular ejection fraction of 30-35%. During the admission he was found to be in atrial fibrillation with a ventricular rate of 110 bpm (Fig. 1) and was given orally a dose of 450 mg of propafenone... (excerpt)Downloads
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