Cardiology News / Recent Literature Review / Last Quarter 2020
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Abstract
Rhythmos 2021;16(1): 14-21.
26th Annual International AF Virtual Symposium, 29-31/1/2021
EHRA online Congress, 23-25/4/2021
ACC Meeting: Atlanta, 15-17/5/2021
EuroPCR online, 18-20/5/201
ESC Digital Congress 27-30/8/2021
TCT Meeting, San Francisco, 22-26/10/2021
Active Myocardial Inflammation is a Powerful Predictor of Recurrent Ventricular Tachycardia (VT) Following Catheter Ablation: VT Ablation Should be Avoided During Active Myocarditis (AM), But is Often of Benefit for Recurrent VT After the Acute Phase of Myocarditis
Among 125 consecutive patients (age 51±14 years, 91% men, LVEF 52%±9%) with myocarditis diagnosed by endomyocardial biopsy (59%) and/or cardiac magnetic resonance (90%), undergoing VT ablation, with all patients showing low-voltage areas (LVA) at electro-anatomical map (97% epicardial or endoepicardial), VT recurrences were documented in 25 patients (20%) by 12 months, and in 43 (34%) by last follow-up (median 63 months). At multivariable analysis, active myocarditis (AM) stage was the only predictor of VT recurrences by 12 months (hazard ratio: 9.5; p < 0.001), whereas both AM stage and wide border zone were associated with arrhythmia recurrences anytime during follow-up. No VT episodes were found after redo ablation was performed in 23 patients with previous (non-active) myocarditis (Peretto G et al, J Am Coll Cardiol 2020;76:1644–1656).
Left Ventricular (LV) Non-Compaction (LVNC): Vigorous Recreational Physical Activity (VPA) May be a Possible Determinant of LV Hypertrabeculation in Asymptomatic Individuals
In PESA (Progression of Early Subclinical Atherosclerosis) study participants (n = 4,184 subjects free of cardiovascular disease), LVNC phenotype prevalence according to the Petersen criterion was significantly higher among participants in the highest VPA quintile (Q5 = 30.5%) than in participants with no VPA (14.2%). The Jacquier and Grothoff criteria were also more frequently fulfilled in participants in the highest VPA quintile (Jacquier Q5 = 27.4% vs no VPA = 12.8% and Grothoff Q5 = 15.8% vs no VPA = 7.1%). The prevalence of the systolic Stacey LVNC criterion was low (3.6%) and did not differ significantly between no VPA and Q5 (de la Chica JA et al, J Am Coll Cardiol 2020;76: 1723–1733).
Interleukin-1β (IL-1β) Measured on Admission is Associated with Risk of Premature Death in Patients with Myocardial Infarction
IL-1β concentration measured at admission in 1,398 patients with ST-segment elevation MI (STEMI) was associated with all-cause mortality at 90 days (adjusted hazard ratio - adjHR: 1.47 per 1 SD increase; p < 0.002). The relation was nonlinear, and the highest tertile of IL-1β was associated with higher mortality rates at 90 days (adjHR: 2.78; p = 0.0002) and at 1 year (adjHR: 1.93; p = 0.005), regardless of the hs-CRP concentration. Significant relationships were equally observed when considering cardiovascular mortality and MACEs at 90 days (adjHR: 2.42; p = 0.002, and adjHR: 2.29; p = 0.004, respectively) and at 1 year (adjHR: 2.32; p = 0.002, and adjHR: 2.35; p = 0.001, respectively) (Silvain J et al, J Am Coll Cardiol 2020;76:1763–1773)... (excerpt)
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