Cardiology News /Recent Literature Review / Last Quarter 2011
Λέξεις-κλειδιά:
cardiology, electrophysiology, cardiac pacing, newsΠερίληψη
The ACC Meeting is slated for 24-27/3/2012 in Chicago
The Athens Cardiology Update 2012 is slated for April 5-7, 2012
The HRS 33rd Meeting will be held in Boston, 9-12/5/12
The ESC Congress will be held in Munich, 25-29/8/2012
ALLHAT Trial: Once Heart Failure Develops in High-Risk Hypertensive Patients, Mortality is High
At a mean follow-up of 8.9 years, of 1761 participants in the ALLHAT trial with incident heart failure (HF) in-trial, 1348 (77%) died. Mortality rates were similar across treatment comparisons, with adjusted 10-year all-cause mortality rates per 100 persons of 83 for chlorthalidone, 86 for amlodipine, and 87 for lisinopril. Mortality was similar for those with preserved (81%) and low ejection fraction (84%). Thus, once HF develops, risk of death is high and consistent across randomized treatment groups. Measures to prevent the development of HF, especially blood pressure control, must be a priority if mortality associated with the development of HF is to be addressed (Piller LB et al, Circulation 2011;124:1811-1818).
Isolated Low HDL-Cholesterol is Associated with Increased Coronary Risk
Data from 220 060 participants (87% Asian) in 37 studies from the Asia-Pacific region indicated low HDL-C (HDL <40 mg/dl in men and <50 mg/dl in women) among 33.1% of Asians vs 27.0% of non-Asians (P<0.001). The prevalence of low HDL-C in the absence of other lipid abnormalities (isolated low HDL-C) was higher in Asians compared with non-Asians: 22.4% vs 14.5%, respectively (P<0.001). After 6.8 years, there were 574 coronary heart disease and 739 stroke events. There was an inverse relationship between low HDL-C with coronary heart disease in all individuals (hazard ratio, 1.57). In Asians, isolated low levels of HDL-C were as strongly associated with coronary heart disease risk as low levels of HDL-C combined with other lipid abnormalities (hazard ratio, 1.67 vs 1.63, respectively). There was no association between low HDL-C and stroke risk (Huxley RR et al, Circulation2011;124:2056-2064)... (excerpt)Λήψεις
Λήψεις
Δημοσιευμένα
Τεύχος
Ενότητα
Άδεια
Authors who publish with this journal agree to the following terms:
a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
