COVID-19 Breakthrough Infections in Vaccinated Individuals
COVID-19 Breakthrough Infections
Περίληψη
Vaccine breakthrough COVID-19 infections are increasingly occurring in fully vaccinated individuals, who may also spread COVID-19 to others. Hence, one is better protected if one wears a mask and maintaining distancing when in indoor public places. Mild infections pose little risk to vaccinated individuals and their contacts, while they may boost the individual immune responses and thus necessitate only monitoring as a precautionary measure. However, higher infectiousness and transmissibility of viral variants remain worrisome. Variants of concern are overrepresented among post-vaccination breakthrough COVID-19 infections. Identifying subgroups at a high risk for severe breakthrough infections is important in prioritizing early preventive treatment or prophylaxis. Despite a strong protection afforded by vaccination against severe disease, breakthrough infections may still advance to severe or critical illness at not-insignificant rates. The age distribution of patients with severe breakthrough infections is skewed towards older age groups and individuals with underlying comorbidities. All these issues and factors modulating the probability of a breakthrough COVID-19 infection in vaccinated people are herein discussed, and a tabulated list of the recommendations of the World Health Organization on COVID-19 infection prevention and control is also presented. Rhythmos 2022;17(1): 92-99.
Λήψεις
Λήψεις
Δημοσιευμένα
Τεύχος
Ενότητα
Άδεια
Authors who publish with this journal agree to the following terms:
a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).