Cardiology News / Recent Literature Review / Second Quarter 2022

Cardiology News

Abstract

ESC Meeting, Barcelona, Spain, 26-29/8/2022

TCT 22, Boston, MA, USA, 16-20/9/22

HCS, 43^rd International Congress of Cardiology, Athens, 20-22/10/22

NY Cardiovascular Symposium 2022, New York, NY, USA, 9-11/12/22

AF Symposium, Boston, MA, USA, 2-4/2/2023

ACC Annual Meeting, New Orleans, LA, USA, 4-6/3/23

EHRA Annual Meeting, Barcelona, Spain, 16-18/4/23

Euro PCR 2023, Paris, 16-19/5/2023

HRS Annual Meeting, New Orleans, LA, USA, 19-21/5/23

Registry Study: In Patients With Multivessel Disease After Revascularization by PCI or CABG, Mildly Decreased Renal Function Did not Increase the Risk of the Primary Composite Outcome (Death, MI, or Stroke) and Mortality / Comparative Outcomes After PCI and CABG Were Similar in the Borderline-Risk Group

Among 10,354 eligible patients in a registry who underwent coronary revascularization, classified into 3 groups (stage I, n = 3,735, normal renal function; stage II, n = 5,122, mild dysfunction; and stage III, n = 1,497, moderate dysfunction), after propensity matching, the risk for primary composite outcome was not different between the stage I and the stage II group (HR: 1.12). However, the risk of the primary outcome was higher in the stage III group than in the stage I group (HR: 1.50). The relative effect of PCI vs CABG for the primary outcome was similar in the matched cohort of each renal function group of stages I, II, and III (Kim TO et al, J Am Coll Cardiol 2022;79:1270-84).

2-Cohort Studies: Long-Term Cumulative BP Was Associated With Subsequent Cognitive Decline, Dementia Risk, and All-Cause Mortality in Cognitively Healthy Adults Aged ≥50 Years / Efforts are Needed to Control Long-Term Systolic BP and Pulse Pressure and Maintain Adequate Diastolic BP

Data from the HRS (Health and Retirement Study, n=9,294, 45% men, median age 65 y) and ELSA (English Longitudinal Study of Ageing, n=7,566, 40% men, median age 62 y) indicated that over a median follow-up of 8 years each, elevated cumulative systolic BP and pulse pressure were independently associated with accelerated cognitive decline (P< 0.001 for both), elevated dementia risk (P< 0.001 for both), and all-cause mortality (P< 0.001 for both), while a significant inverse association was observed for diastolic BP. Strong dose-response relationships were identified, with similar results for the 2 cohorts. (Li C et al, J Am Coll Cardiol 2022;79:1321–35).

The BIOSIGNAL Study: MR-proANP is a Valid Biomarker to Determine Risk of Newly Diagnosed Atrial Fibrillation (NDAF) and MACE in Patients With Acute Ischemic Stroke (AIS) and Can Be Used as a Decision Tool to Identify Patients for Prolonged Cardiac Monitoring

Among 1,759 patients Log₁₀MR-proANP levels were associated with cardioembolic (CE) stroke (OR: 7.96; risk ratio: 3.12), as well as NDAF (OR: 35.3; risk ratio: 11.47), and MACE (subdistributional HR: 2.02) during follow-up. The model to predict NDAF including only age and MR-proANP levels had a good discriminatory capacity with an area under the curve of 0.81, was well calibrated, and yielded higher net-benefit compared with validated scores to predict NDAF (AS5F score, CHA₂DS₂-VASc score) (Schweizer J et al, J Am Coll Cardiol 2022;79: 1369–81)... (excerpt)